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Patrick Darken Selected Research

Formoterol Fumarate (Oxis)

1/2022Benefits of Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate on COPD Exacerbations, Lung Function, Symptoms, and Quality of Life Across Blood Eosinophil Ranges: A Post-Hoc Analysis of Data from ETHOS.
8/2021Corrections to: Efficacy of budesonide/glycopyrronium/formoterol metered dose inhaler in patients with COPD: post-hoc analysis from the KRONOS study excluding patients with airway reversibility and high eosinophil counts.
8/2021Benefits of budesonide/glycopyrrolate/formoterol fumarate (BGF) on symptoms and quality of life in patients with COPD in the ETHOS trial.
6/2021Efficacy of budesonide/glycopyrronium/formoterol metered dose inhaler in patients with COPD: post-hoc analysis from the KRONOS study excluding patients with airway reversibility and high eosinophil counts.
1/2021Reduced All-Cause Mortality in the ETHOS Trial of Budesonide/Glycopyrrolate/Formoterol for Chronic Obstructive Pulmonary Disease. A Randomized, Double-Blind, Multicenter, Parallel-Group Study.
1/2021Improvements in lung function with budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler versus dual therapies in patients with COPD: a sub-study of the ETHOS trial.
1/2021Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Improves Exacerbation Outcomes in Patients with COPD without a Recent Exacerbation History: A Subgroup Analysis of KRONOS.
1/2020Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD.
1/2020Pharmacokinetics of budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler formulated using co-suspension delivery technology after single and chronic dosing in patients with COPD.
1/2020Efficacy of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Versus Other Inhaled Corticosteroid/Long-Acting Muscarinic Antagonist/Long-Acting β2-Agonist (ICS/LAMA/LABA) Triple Combinations in COPD: A Systematic Literature Review and Network Meta-analysis.
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Patrick Darken Research Topics

Disease

37Chronic Obstructive Pulmonary Disease (COPD)
10/2023 - 06/2003
5Asthma (Bronchial Asthma)
01/2022 - 09/2007
2Obstructive Lung Diseases (Obstructive Lung Disease)
01/2021 - 07/2014
2Allergic Rhinitis
10/2007 - 09/2007
1Dyspnea (Shortness of Breath)
08/2021
1Lung Diseases (Lung Disease)
08/2021
1Pneumonia (Pneumonitis)
01/2020
1Nasopharyngitis
10/2018
1Respiratory Tract Infections (Respiratory Tract Infection)
10/2018
1Perennial Allergic Rhinitis
10/2007
1Ventricular Tachycardia
06/2003
1Tachycardia (Tachyarrhythmias)
06/2003

Drug/Important Bio-Agent (IBA)

24Formoterol Fumarate (Oxis)FDA Link
01/2022 - 09/2014
24Glycopyrrolate (Glycopyrronium Bromide)FDA LinkGeneric
01/2022 - 07/2014
16Adrenal Cortex Hormones (Corticosteroids)IBA
10/2023 - 09/2003
11Budesonide (Pulmicort)FDA LinkGeneric
01/2022 - 01/2018
11SuspensionsIBA
01/2020 - 11/2016
9budesonide-glycopyrrolate-formoterol fumarate drug combinationIBA
10/2023 - 10/2018
9Muscarinic AntagonistsIBA
10/2023 - 01/2017
5Tiotropium Bromide (Spiriva)FDA Link
01/2022 - 07/2014
3Salmeterol Xinafoate (Serevent)FDA Link
01/2018 - 06/2003
2fluticasone furoateFDA Link
10/2023 - 01/2023
2vilanterolIBA
10/2023 - 01/2023
2GSK573719IBA
10/2023 - 01/2023
2Bronchodilator Agents (Bronchodilators)IBA
11/2016 - 07/2014
2ciclesonideFDA Link
10/2007 - 09/2007
2Hydrocortisone (Cortisol)FDA LinkGeneric
10/2007 - 09/2007
1GlucocorticoidsIBA
01/2020
1Anti-Bacterial Agents (Antibiotics)IBA
01/2020
1N 30IBA
10/2018
1Beclomethasone (Beclometasone)FDA Link
10/2007
1Fluticasone-Salmeterol Drug Combination (Advair)FDA Link
09/2007
1Fluticasone (Cutivate)FDA LinkGeneric
09/2003
1Adrenergic Agents (Adrenergic Drugs)IBA
06/2003

Therapy/Procedure

27Metered Dose Inhalers (Metered Dose Inhaler)
01/2022 - 07/2014
18Therapeutics
10/2023 - 01/2018
5Dry Powder Inhalers
01/2020 - 01/2016
3Nebulizers and Vaporizers (Inhaler)
01/2021 - 09/2003
1Inhalation Spacers
01/2018